CARDIOVASCULAR AND RENAL DRUGS ADVISORY COMMITTEE

BRIEFING INFORMATION

October 14-15, 1999

VOLUME 1

Tab 1 Tirofiban Medical and Statistical Review

Pages 1 - 100

Pages 101 - 200

Pages 201 - 300

Pages 301 - 397

VOLUME 2

Tab 1 - Eptifibatide Medical Review (PURSUIT Study)

Tab 2 - Epitifibatide Medical Review (PERIGREE Study)

Tab 3 - Epitifibatide Medical Review (PRIDE Study)

Tab 4 - Epitifibatide Medical Review (IMPACT I and II Studies, IMPACT High-Low Study)

Part 1

Part 2

Tab 5 - Meta-analysis of IIb/IIIa antagonists

 

Volume 3

Tab 1 - Tirofiban Clinical Pharmacology Review

Tab 2 - Eptifibatide Statistical Review (IMPACT II Study)

Tab 3 - Epitifibatide Statistical Review (PURSUIT Study)