|Overall in studies
1027 and 1028, As the number of susceptible drugs in the OBT increased,
reflected in an increased overall susceptibility score, the percent of
subjects that achieved <400 copies/mL increased in the MVC arms (orange
and blue) to 70% if 3 or more susceptible drugs in OBT.
|In the placebo arm
(red), response rates were <20% with less than 2 active drugs, but
increased to 61% when subjects had 3 or more susceptible drugs in OBT.