Mean (median) Change in CD4
counts from Baseline LOCF24

63 (29)

N=12

99 (103)

N=14

70 (70)

N=16

NR/NP

43 (14)

N=11

63 (58)

N=61

47 (25)

N=48

Dual-Mixed

76

N=1

52 (31)

N=20

60 (33)

N=18

CXCR4

38 (11)

N=122

128 (110)

N=48

123 (93)

N=72

R5

Placebo

N=146

BID

N=143

QD

N=154

Tropism at
Failure

An examination of
CD4+ cell counts by Tropism at Failure showed that the mean and median change
in CD4 cell counts from baseline using last observation carried forward was
lower in subjects with X4 and dual/mixed tropic virus than those with
R5-tropic virus