|GSS and PSS scores
were used to determine susceptibility.
|A score of 1 was
given for each susceptible drug in OBT. Therefore, the higher the GSS and
PSS score – the more susceptible drugs in OBT
|•GSS and PSS scores were balanced across the three treatment
groups in both studies with Median GSS=1 and PSS=2
|•67% of subjects had on overall susceptibility scores <2
meaning they had 2 or less active drugs their in OBT
|•30% had only one potentially active drug in OBT and
|•14% of subjects had no potentially active drug in their
|•Consistent with a heavily treatment-experienced population.