Postural Hypotension During Double-Blind Period
Studies 1027 and 1028
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Dose-limiting AE during phase 1 at doses of
600-1200 mg
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MedDRA terms: Hypotension, orthostatic
hypotension, dizziness, syncope
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109 Patients:
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–
MVC QD
51 (12%)
–
MVC BID
39 (9%)
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Placebo
19 (9%)