6
Drug Safety and Risk Management Advisory Committee 
February 9, 2006
ADHD overview, continued
nMale:female ratio from 4:1 to 9:1 (DSM-IV)
nEstimates of prevalence in school age children range from 3-5% (DSM-IV) to 8-12% (Biederman and Faraone 2005)
nEtiology not known (environmental, genetic, developmental, family dysfunction)
nDiagnosis is clinical (no pathognomonic physical or laboratory findings)
nDiagnosis applies to different levels of severity
n