Key Question for Pediatric Suicidality Data:
Is there a causal link between antidepressant drug use and
suicidality in pediatric patients with major depressive
disorder or other psychiatric disorders?
Critically important question to answer
Also important to answer in a careful, thoughtful manner
Erring in either direction would have adverse
Missing a signal of increased risk of suicidality would
result in greater comfort than is warranted in the safety
of these drugs in treating pediatric depression.
A premature decision on the strength of the signal
could result in the overly conservative use of these
drugs, or their lack of availability entirely for the