CE-17
Different
Anti-Anginal Pharmacodynamics of Ranolazine vs Atenolol
Effects on RPP in RAN080
Effects on RPP in RAN080
7,500
10,000
12,500
15,000
17,500
20,000
22,500
25,000
27,500
p = 0.35
p <
0.001
p < 0.001
p = 0.005
p <
0.001
p <
0.001
At rest
End exercise
N = 154; 3-period crossover; Rousseau et al, 1994.
Placebo
Ranolazine IR 400 mg tid
(1741 ± 1026 ng base/mL)
Atenolol 100 mg qd
7,500
10,000
12,500
15,000
17,500
20,000
22,500
25,000
27,500
