FOOD AND DRUG ADMINISTRATION
CENTER FOR BIOLOGICS EVALUATION AND RESEARCH
VACCINES AND RELATED BIOLOGICAL PRODUCTS ADVISORY COMMITTEE
1. What strains should be recommended for the antigenic composition of the 2003-2004 inactivated influenza virus vaccine based on:
1) the epidemiology and antigenic characteristics of influenza virus strains circulating in human populations,
2) the serologic responses to circulating influenza viruses of persons immunized with current influenza virus vaccines, and
3) the availability of suitable vaccine candidate strains?