Studies 437 and 438 Median Change from Baseline in HBV DNA

aWilcoxon Rank-Sum Test

pɘ.001a

HBeAg-

pɘ.001a

HBeAg+

PLB

ADV 10

-4

-3

-2

-1

0

PLB

ADV 10

Weeks

0 4 8 12 16 20 24 28 32 36 40 44 48

-4

-3

-2

-1

0

0 4 8 12 16 20 24 28 32 36 40 44 48

log10 copies/mL

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