Chronic Hepatitis BA Global Healthcare Issue

1Lok AS, Gastroenterology 2001

2Lee W, NEJM 1997

• 400 million with chronic hepatitis B worldwide1

  • HBeAg+
  • HBeAg–

• 25-33% develop progressive disease

  • Cirrhosis or hepatocellular carcinoma
  • 1 million deaths per year

• 1.25 million with chronic hepatitis B in US2

  • 17,000 hospitalizations and 5,000 deaths per year
  • 6th leading indication for adult liver transplantation

• 400 million with chronic hepatitis B worldwide1
  • HBeAg+
  • HBeAg–

• 25-33% develop progressive disease
  • Cirrhosis or hepatocellular carcinoma
  • 1 million deaths per year

• 1.25 million with chronic hepatitis B in US2
  • 17,000 hospitalizations and 5,000 deaths per year
  • 6th leading indication for adult liver transplantation

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