Food and Drug Administration

Gastrointestinal Drugs Advisory Committee

March 19, 2002

Chemoprevention of Colorectal Cancer

Slides

Mechanisms and Epidemiology of Colon Cancer, Anil K Rustgi,MD, University of Pennsylvania   ppt   htm

Colorectal Cancer Screening, David Lieberman MD, Oregon Health Sciences University   ppt   htm

Overview of Colorectal Chemoprevention Trials, Bernard Levin MD, The University of Texas M. D. Anderson Cancer Center   ppt   htm

The Chemoprevention of Sporadic Colorectal Cancer, Issues Surrounding a Benefit/Risk Analysis in Clinical Trials, Mark Avigan MD CM, FDA   ppt   htm

OPEN PUBLIC HEARING

Chemoprevention of Colorectal Cancer: Design Considerations and Implications, Robert S Sandler MD MPH, University of North Carolina at Chapel Hill  ppt   htm

O'Shaughnessy, Joyce A. et al, "Special Article, Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated new Agent Development, Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia,"  Clinical Cancer Research, Vol. 8, pp 314-346, February 2002.

Chemoprevention of Colorectal Cancer Trial Design, Colorectal Cancer Network   pdf (New 04/01/02)