Table of Contents
Issues in Selection of Deltas in Non-Inferiority Trials : Acute Bacterial Meningitis and Hospital-Acquired Pneumonia
Introduction
Clinical Trials
Non-Inferiority Trials
Non-Inferiority Margins
Components of Delta
Components of Delta - Delta 1
Components of Delta - Delta 2
Components of Delta - various diseases
Components of Delta Meningitis and HAP
Components of Delta Meningitis and HAP
Historical Data - Meningitis
Historical Data - Meningitis
Historical Data - HAP
Historical Data - HAP
Historical Data - HAP
Components of Delta Meningitis
Components of Delta HAP
Components of Delta Meningitis and HAP
Consequences of Failure
Practical Issues
Clinical Trial Implications: Sample size per arm to achieve 80% power
Epidemiology of Meningitis*
Epidemiology of Meningitis
Epidemiology of HAP
Epidemiology
Recent Trials
Clinical Trial Implications: Sample size per arm to achieve 80% power
Components of Delta Meningitis and HAP
The Balance
|
Author: Infectious Diseases
|