Efficacy of the Combination: Meta-Analyses

1/29/02


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Table of Contents

Efficacy of the Combination: Meta-Analyses

Speakers for This Morning

Patient Group Comparisons

Is the Combination More Effective than Pravastatin Alone?

Event Rates for Primary Endpoints in LIPID and CARE

Accounting for Baseline Risk Factors

Meta-Analysis of these Pravastatin Secondary Prevention Trials

Trial Commonalities

Meta-Analysis Endpoints Considered

Meta-Analysis Models

Relative Risk Reduction Cox Proportional Hazards All Trials

Relative Risk Reduction Cox Proportional Hazards LIPID and CARE

Relative Risk Reduction Cox Proportional Hazards LIPID and CARE

Meta-Analysis Models

Model 2 Hierarchical, Random Effects

Model 2 Hierarchical, Random Effects

Model 2 Hierarchical, Random Effects

Combination is More Effective than Either Agent Alone

Model 2: Fatal or Non-Fatal MI

Meta-Analysis Models

Model 3: Fatal or Non-Fatal MI

Conclusion of Hazard Analysis over Time

PPT Slide

Author: mmedia3