Epidemiology of Adenovirus Infections

7/27/01


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Table of Contents

Epidemiology of Adenovirus Infections

Clinical Manifestations

Adenovirus Transmission

Adenovirus Pneumonia

Adenovirus Infections in Immunocompromised Hosts

Adenoviruses in Bone Marrow Transplant Recipients

Adenovirus disease in BMT recipients

1985 Seattle Study

1994 Milwaukee Study

1994 Milwaukee Study

1999 Kentucky Study

2000 Bristol Study

Solid Organ Transplantation

Congenital Immunodeficiency Syndromes

Adenoviruses in AIDS Patients

Adenoviruses in Cancer Patients

Treatment

Cidofovir

Therapy

Immunotherapy

Immune Responses Against Adenoviruses

Adenovirus-specific T cell Responses

Pathogenesis

Adenovirus Persistence

Transmission of adenovirus from solid organ transplants

Reactivation of adenovirus in BMT recipients

Mechanism of Persistence

Adenovirus Early Region 3

Adenovirus Persistence

Are Lymphocytes a Reservoir?

Adenovirus Reservoirs

Live Adenovirus Vaccine

RCA in Adenovirus Gene Therapy Vectors

RCA in Adenovirus Gene Therapy Vectors

Issue of Recombination

Author: Thomas Jefferson University