FOLLOW-UP: OBSERVATION VS. THERAPY

Patients with Pap smears interpreted as LSIL may

have colposcopy directly

if reliable and have the ability to be followed, may be followed by

repeat smears at 4 to 6 months.

A meta-analysis of women with LSIL Pap tests had

a pooled rate of regression reported as 47.39%, with a very low

risk of invasive carcinoma, varying from 0.00% to

0.74% of the patients.

Melnikow J et al. Obstet Gyne 1998;92:727-35