Natural history of CIN: summary

CIN 1 57% 32% 11% 1%

CIN 2 43% 35% 22% 5%

CIN 3 32% < 56% -- ᡄ%

Progress Progress

Regress Persist to CIS to invasion

64 studies, 274 carcinomas, 15,473 CIN cases

Followup ə-12 years

Östör AG, Int J Gyne Path 1993;12:186-192