PPT Slide

Gammaretrovirus

Lentivirus

• Integration into host chromosome

• No viral genes expressed in

target cells

• Transduces

non-dividing cells

• Efficient adaptation

to SIN technology

• Inefficient adaptation

to SIN technology

• Potential for recombination resulting

in replicating virus with possible pathogenicity

• Can’t transduce

non-dividing cells

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