PPT Slide
- The adverse effects of treprostinil were related to its pharmacologic properties and were generally not serious. Serious AEs occurred with similar frequency in the placebo and treprostinil groups.
- Localized infusion site pain and reactions were common, but generally were manageable and did not limit increases in dose or require the withdrawal of treatment.
- Treprostinil was not associated with any significant changes in laboratory parameters or end-organ toxicity.