Among PAH Patients with Anemia

• No evidence for increase in bilirubin
• No associated decrease in WBCs or platelets
• No increase in eosinophils above the ULN
• No premature withdrawal due to anemia
• Blood transfusions in 4 patients (2.4%)
  • 1 epistaxis, 2 GI bleeding, and 1 anemia
  • All 8 PC studies:

1.8% on bosentan

1.0% on placebo

9081.01

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