Overall ExposurePAH Patients

0

90

180

270

40

0

May 31, 2001 cut off

360

540

630

100

60

Days

80

Percent of Patients

20

450

Bosentan

> 3 months 191 (81.3%)> 6 months 128 (54.5%)> 9 months 41 (17.4%)ᡄ months 28 (11.9%)

ᡊ months 12 (5.1%)

137.2 patient-years

N = 235

9072.01

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