Reasons for DeathAC-052-351 and AC-052-352

Cardiac failure [n (%)]

Aggravated PHT

Pneumonia

Pulmonary hemorrhage

Sepsis

Total deaths

Placebo

(N = 80)

0

2 (2.5)

0

0

0

2 (2.5)

2 (1.2)

0

1 (0.6)

1 (0.6)

1 (0.6)

4 (2.4)

Bosentan

(N = 165)

All deaths occurring during the study or within 28 days of treatment end

9066.01

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