Most Frequent (? 5%) Treatment-emergent AEsAC-052-351 and AC-052-352

Abnormal hepatic func (%)

Leg edema / edema

Flushing

Nasopharyngitis

Hypotension

% with ? 1 AE

Placebo

(N = 80)

2.5

8.8

5.0

7.5

3.8

93.8

With a placebo-subtracted difference of ? 2%

8.5

13.9

9.1

10.9

6.7

94.5

Bosentan

(N = 165)

6.0

5.2

4.1

3.4

2.9

0.7

Placebo-subtracted

9061.01

Previous slide

Next slide

Back to first slide

View graphic version