Open-label Extension AC-052-353
Bosentan
62.5 mg bid
Bosentan 125 mg bid
1 - 4 weeks
Bosentan 250 mg bid
Bosentan 62.5 mg bid
Assessments
Walk test at Week 4
WHO class each 6 months
Patients
8 / 11 ex-placebo
21 / 21 ex-bosentan
3/31/01 cut off
9043.01
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