Maintenance of Efficacy Walk Test Up to 28 Weeks
50
75
100
0
AC-052-351
Bosentan 125 mg bid
n = 21
n = 20
n = 6
25
Weeks
AC-052-352
50
75
100
0
25
0
4
8
12
16
20
24
28
Bosentan 125/250 mg bid (n = 35)
Placebo (n = 13)
Change from Baseline (meters)
9493.01
Mean ? SEM
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