Improvement in WHO ClassEnd of Period 1
Pbo
(n = 69)
Improved
Treatment effect
95% CL
Bos
(n = 144)
Pbo
(n = 11)
Bos
(n = 21)
43%
9%
AC-052-351
AC-052-352
42%
30%
Treatment effect of both studies combined 14.9% (1.3%, 27.0%)
33.8%
?5.6%, 58.0%
11.9%
?2.9%, 25.2%
9039.01
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