Change in Borg Dyspnea Index Mean Treatment Effect
Treatment difference (score)
0
?1
?2
?3
0.5
?0.5
?1.5
?2.5
?3.5
Bos
Pbo
125 mg bid
21
11
AC-052-351
125 mg bid
AC-052-352
74
69
250 mg bid
70
69
125/250 mg bid
144
69
Mean (95% CL)
?1.6 (?3.1, 0.0)
?0.4 (?1.1, 0.3)
?0.9 (?1.6, ?0.2)
?0.6 (?1.2, ?0.1)
9035.02
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