6-minute Walk Test Mean Treatment Effect
Treatment difference (meters)
?20
20
40
60
80
100
120
0
140
Bos
Pbo
125 mg bid
21
11
AC-052-351
125 mg bid
AC-052-352
74
69
250 mg bid
70
69
125/250 mg bid
144
69
Mean (95% CL)
75.9 (12.5, 139.2)
34.6 (6.2, 63.1)
54.3 (27.3, 81.4)
44.2 (21.4, 67.0)
P = 0.0002
P = 0.0205
(P = 0.0001)
(P = 0.0107)
9028.02
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