Main Exclusion Criteria
- PAH due to other causes (eg, congenital HD, HIV, cirrhosis, thromboembolic, COPD…)
- SSc/PAH with mod / severe interstitial fibrosis
- Systolic BP < 85 mmHg
- ALT / AST > 3 x ULN
- Hb / Hct > 30% below the LLN
- PAH treatment modified within 1 month of screening (excluding anticoagulants)
- Received epoprostenol within 3 months of screening