Difficulties in showing a dose-response with locally-acting nasal sprays and aerosols for allergic rhinitis

7/20/01


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Table of Contents

Difficulties in showing a dose-response with locally-acting nasal sprays and aerosols for allergic rhinitis

Nasal sprays and aerosols

Allergic rhinitis study design

Allergic rhinitis study design

Experience with three drug substances

Drug A: Dose-ranging study with a solution nasal spray

Drug B: Dose-ranging study with a suspension nasal spray

Drug B: Comparative study with a suspension nasal spray and aerosol

Drug C: Dose-ranging study with a suspension nasal spray

Drug C: Comparative dose-ranging study with a suspension nasal spray and aerosol

Summary comments

Author: Badrul A. Chowdhury