American Academy of Pediatrics Committee on Children with Disabilities Perspective on

5/21/01


Click here to start


Table of Contents

PPT Slide

American Academy of Pediatrics Committee on Children with Disabilities Perspective on

The Big Picture

In general, studies must address

Studies must also address

This topic presents an unusual and complex set of issues

Issues continued

Long-standing anecdotal knowledge use of anticholinergics in pediatric populations

ASSESSMENT Anterior Drooling represents only one element in the continuum of oral performance impairment

Factors that need to be assessed to determine etiology

Therapies Hierarchical, least invasive first

What does this population actually look like?

The gap between incidence and prevalence of DD/MR is closing This translates into increasing

Increasing Complexity Most of the children we see that need these agents have

These kids have FRAGILE BRAINS

The average child referred to us

General medical issues related to the use of antimuscarinics

How can adverse events be assessed in this population?

BEHAVIOR how do you quantitatively assess? Behavior Equivalents

Behavior Assessment and Rating Scales All children in studies must have a

Do not just study children with Cerebral Palsy without cognitive disability or language problems

Safe and ethical conduct of studies

Safe and ethical conduct continued

Safe and ethical conduct continued

Other recommendations for studies

Other recommendations continued

Pediatric Formulations

Pediatric Formulations Continued

Guidance for dosing and management on product labels Discussion of

Discussion continued

Thank you for your kind attention and consideration of these recommendations

Author: OIR