Perinatal HCV TransmissionOccurs Peripartum

• 441 mother-child pairs in the UK and Ireland

• Overall perinatal transmission rate 6.7%

• 3.8 times higher transmission from HIV coinfected women (no concurrent HIV transmission)

• Negative PCR common in infected newborns

• Mode of Delivery

  • Vaginal 7.7%
  • Emergency C/S 5.9%
  • Elective C/S 0% adjusted OR 0 (0-0.87)

Gibb DM, Lancet 2000;356:904

Early rupture of membranes

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