Adenoviral Infections in BMT Patients

• Adenoviral infection 20.9%, adenoviral disease 6.5% in 201 BMT patients (Flomenberg 1994)

• Risk Factors for Disease

  • Isolation of virus from multiple sites
  • Moderate to severe aGVHD
  • Infection more common in children (31.3% vs. 13.6%)

• Time of onset of post transplant

  • Pediatric, mean ណ days
  • Adults, mean > 90 days
  • ??Significance of primary infection

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