Tenth Congress of the International Psychogeriatric Association Nice, France September 9 – 14, 2001 Pharmacy and Therapeutics Committee Mild Cognitive Impairment: Definition, Diagnosis and Prognosis

3/16/01


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International Psychogeriatric Association

Tenth Congress of the International Psychogeriatric Association Nice, France September 9 – 14, 2001 Pharmacy and Therapeutics Committee Mild Cognitive Impairment: Definition, Diagnosis and Prognosis

Mild Cognitive Impairment: A Broad Perspective

“The MCI diagnostic

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“ The term MCI was first used in the description of GDS stage 3” 1, 2

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Equilibrium and Limb Coordination in Mild Cognitive Impairment and Mild Alzheimer’s Disease Franssen, et al. J Am Geriatr Soc., 47: 463-469, 1999.

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Can MCI be clearly defined in a clinical setting?

Are there valid criteria for a diagnosis of MCI?

Can MCI be distinguished from Alzheimer’s disease and other causes of dementia?

What outcome measures are appropriate to use in clinical drug trials conducted in MCI?

Should clinical drug trials in MCI incorporate any special features in their design?

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Can MCI be clearly defined in a clinical setting?

Are there valid criteria for a diagnosis of MCI?

Can MCI be distinguished from Alzheimer’s disease and other causes of dementia?

What outcome measures are appropriate to use in clinical drug trials conducted in MCI?

Should clinical drug trials in MCI incorporate any special features in their design?

Author: FDA.CDER