Pneumococcal Susceptibilities: US 1998CDC – 7 Cities – 16.5 million population

% Susceptible (NCCLS breakpoints)

Pen S Pen I Pen R

(n=2636) (n=356) (n=483)

Amoxicillin 100 98.2 17.8

Cefuroxime 99.9 65.2 0

Cefotaxime 99.9 85.3 5.9

Ceftriaxone 100 97.2 57.6

Erythromycin 96.8 64.9 38.7

Tetracycline 98.7 80.9 74.5

TMP-SMX 93.4 50.6 7.7

Whitney et al. NEJM 2001;343:1917

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