HBV DNA Detection in anti-HBc+ HBsAg- US blood donations Kleinman et al. AABB 2001
5121 anti-HBc-only donations from 5 REDS sites tested
1231 anti-HBc+, anti-HBs IU/mL by Prism
395 rep samples screened by PCR ( IU/mL) w/ confirmation by 2 PCR assays on sep aliquot
4 HBV DNA+ detected (4/107 anti-HBs-neg)
- HBV DNA load 10-100 copies/mL
Project 1 HBV DNA+ per 48,955 Tx units, similar to projected yield of HBV DNA+ pre-HBsAgWP units