Time-dependent concentrations in skin strippings and follicles

Issues - SC Surrogate For Target Site

(Schaefer, H. and Redelmeir, T.E. (eds) Skin Barrier, Principles of Percutaneous Absorption, Kruger Publishers, p.198, 1996)

• Stratum corneum concentrations do not predict follicular concentrations. DPK cannot be used to assess BA/BE for follicularly delivered drugs.

Next slide

Back to first slide

View graphic version