Rate of Acute Infusion-Related Adverse Events by Week on Treatment

>Wk 2

Wk 2

0.0

0.5

1.0

1.5

2.0

2.5

Number of events per

patient-week of exposure

Grade 3/4 Events

All Events

Wk 1

Wk 1

Wk 1

Wk 2

Wk 2

>Wk 2

>Wk 2

Rigors

Fever

Hypotension

Integrated Safety Database (N=149)

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