Systemic Exposure of Topical Tacrolimus

4/23/01


Click here to start


Table of Contents

Systemic Exposure of Topical Tacrolimus

Adult PK Studies In NDA

Adult Studies (0.1% Protopic™ )

Systemic Exposure of 0.1% Protopic™ From PK Studies In Adults

Clinical Trials With Concentrations ? 5ng/mL From Random Sampling In Adults

Key Findings From a Study With 0.3% Tacrolimus Ointment In Adults

Pediatric PK Studies in NDA

Pediatric Studies (0.1% Protopic™ )

Systemic Exposure of 0.1% Protopic™ From PK Studies In Pediatrics

Key Findings From a Study with 0.3% Tacrolimus Ointment In Pediatrics

Highest Observed Concentrations in Clinical Trials From Random Sampling (Age 2-6yrs)

Systemic Absorption of Topical Tacrolimus Compared to Oral Tacrolimus

Conclusions

Author: Veneeta Tandon PhD