Pathogenesis of Glutathione Deficiency: Cytokine Selection (Slide 2)

“Antigen-presenting cells (APC) -- macrophages, dendritic cells, and B cells -- are central to the development of either Th1 or Th2 immunity because antigen presentation and recognition are required to initiate responses.”

“...GSH depletion inhibits Th1-associated cytokine production and/or favors Th2-associated responses.”
- Peterson, J., Proc. Natl. Acad. Sci. U S A 1998, Mar. 17;95(6): 3071-3076.

“Antigen-presenting cells (APC) -- macrophages, dendritic cells, and B cells -- are central to the development of either Th1 or Th2 immunity because antigen presentation and recognition are required to initiate responses.”