Pathogenesis of Glutathione Deficiency: Cytokine Selection (Slide 1)

• “Glutathione Levels in Antigen-presenting Cells Modulate Th1 Versus Th2 Response Patterns.” (Title of Article)

  • “...the Th1 pattern is characterized by interleukin 12 (IL-12) and interferon ? (IFN-?) production and the up-regulation cell-mediated, e.g.,delayed hypersensitvity, (DTH) responses.”
  • “The Th2 response pattern is characterized by IL-4 and IL-10 production and up-regulation of a variety of antibody responses.”

• Peterson, J., Proc. Natl. Acad. Sci. U S A 1998, Mar. 17;95(6): 3071-3076.

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