PPT Slide

Lymphocyte Proliferation Assay

• In vitro correlate of cell mediated immunity which is important in the control of viral and intracellular bacterial infections

• Quantitates the response of T cells to a variety of stimuli including mitogens, alloantigens and specific recall antigens

• HIV infected patients tend to lose LPA responses in the order of recall antigen, alloantigen, mitogen

• Strong LPA responses to HIV antigens associated with control of viral replication.

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