Suicidal Behavior Reports
Total of 168 reports of suicidal behavior (1982 to April 30, 1999)
- 104 reported suicide attempts
- 64 reports of completed suicides
Overall suicide reports were poorly documented; none had psychological autopsy
No apparent dose relationship
Ratio of M/F is 5 to 1 for completed suicide reports
In summary: None of the 168 reports implies direct causality between suicidal behavior and Accutane administration, at the individual case level