Indinavir and virologic efficacy
Some (but not all) studies show, in retrospective, relationships between indinavir pharmacokinetics and HIV-1 RNA response.
These relationships have mainly been established in NRTI-pretreated patients.
Reported pharmacokinetic parameters are AUC, Cmin, and Cmax (all correlated).
No clear data on such relationships when indinavir is used in combination with (low dose) ritonavir.