Assessing Cardiac Safety of Second-generation Antihistamines

5/23/01


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Assessing Cardiac Safety of Second-generation Antihistamines

Yes Coadministration of drugs that block delayed rectifier potassium current, IKr

Intentional or accidental overdose

Cloned human channels, such as HERG, Kv1.5, expressed in a human cell line

Author: FDA.CDER