Food and Drug Administration

Transmissible Spongiform Encephalopathies Advisory Committee

June 2, 2000


Topic 2.  Possible Effects of Leukoreduction on CJD Risk

Leukoreduction of blood: Introduction, background, recent recommendations and prospects for implementation, J-H Lee MD, FDA  pdf

Leukoreduction of blood: Techniques, results, and theoretical applications to TSE agents in blood, J Vostal MD PhD, FDA   pdf

Montrasio, Fabio, et al, "Impaired Prior Replication in Spleens of Mice Lacking Functional Follicular Dendritic Cells," Science, vol 288, May 19, 2000, pp 1257-1259.