Rationale for UprimaŽ Treatment of ED
ED is associated with a number of diseases and conditions
Drugs with different modes of action are desirable as with other disorders with complex pathophysiology, e.g., hypertension, depression
Current therapies are limited:
- No drug is effective in all patients
- Each drug has its own unique adverse event profile
- The currently approved agents work by peripheral mechanisms
Treatment is strongly influenced by couple and physician choice
New drugs with different mechanisms offer significant potential benefits