Carbamazepine in Dementia

• Uncontrolled Studies

? N = 26

? All positive

• Controlled Studies

? 1 negative (flawed), n = 19

? 2 positive (n = 75)

? Consistent benefit ᡪ%

? Lability, aggression

? Usual dose 300 mg/d

? Concerns about SE’s, drug-drug interactions

Tariot et al 1998, 1999

Previous slide

Next slide

Back to first slide

View graphic version