PERIPHERAL & CENTRAL NERVOUS SYSTEM ADVISORY COMMITTEE

JANUARY 28, 2000

Novantrone (mitoxantrone) indicated in Multiple Sclerosis

NDA 21-120

Briefing Information

FOOD AND DRUG ADMINISTRATION

IMMUNEX

The statements contained in this document are those of the product's sponsor, not FDA, and FDA does not necessarily agree with the sponsor's statements. FDA has not made a final determination about the safety or effectiveness of the product described in this document.