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Figure 1

This figure shows a flow chart demonstrating the process used to determine how many protocols met the criteria for listing in ClinicalTrials.gov. The boxes are connected by downward-pointing arrows, as follows:

Box 1: 2062 protocols submitted

Box 2: 1361 protocols for serious or life threatening diseases and conditions.

Box 3: 1088 phase 2, 3, or 4 protocols

Box 4: 688 protocols with primary or secondary efficacy endpoints.

Box 5: 239 (35%) trials listed in ClinicalTrials.gov.

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